Title : Prevalence and pattern of dyslipidemia and its associated factors among patients of type 2 Diabetes Mellitus in India
Abstract:
Background: Dyslipidemia is a common comorbidity in type 2 diabetes mellitus (T2DM) and contributes to cardiovascular disease. Understanding the associations between anthropometric indices and lipid parameters is important for risk stratification.
Methods: A cross-sectional study was conducted in adults with T2DM. Data collected included age, body mass index (BMI), waist circumference (WC), lipid parameters (total cholesterol [TC], LDL-C, HDL-C, triglycerides [TG], TC/HDL ratio), and comorbidities (hypertension, dyslipidemia, coronary artery disease [CAD], chronic kidney disease [CKD]). Lipid levels were classified using standard criteria. Pearson’s correlation was used to assess associations between anthropometric measures and lipid parameters.
Results: A total of 51 patients with T2DM (22 males, 29 females) were included. Median age was 59 years and median BMI was 26.2 kg/m². Comorbidities included hypertension (58.8%), dyslipidemia (76.5%), CAD (9.8%), and CKD (9.8%). Median lipid values were TC 166 mmol/L, LDL-C 92.2 mmol/L, HDL-C 49 mmol/L, and TG 214 mmol/L. Hypertriglyceridemia (60.8%) and low HDL-C (17.6%) were the most frequent lipid abnormalities. BMI showed an inverse correlation with TC (r = –0.2823, p = 0.047), and WC showed an inverse correlation with HDL-C (r = –0.2893, p = 0.0395). No other significant associations were observed.
Conclusion: Among adults with T2DM in India, hypertriglyceridemia and low HDL-C were the predominant lipid abnormalities. BMI and WC demonstrated differential associations with lipid fractions, highlighting the importance of assessing both general and central adiposity in cardiovascular risk evaluation.