An excessive consumption of refined carbohydrates and a low intake of dietary fibres (DFs), notably from vegetables, has elevated the risk of diabetes, cardiovascular disease, and other illnesses. The incidence of chronic diseases is increasing, with the number of diabetics predi [....] » Read More
MASH is a growing health concern. Better understanding of factors that prevent hepatic lipid accumulation may help design new strategies to prevent or treat MASH. We have previously shown that adipocyte MTP regulates intracellular lipolysis by inhibiting ATGL activity. Here, we s [....] » Read More
Background: Eating speed is thought to be a novel risk factor for the development of diabetes. Our previous study reported that the DNA region related to the SOCS3 gene, which encodes suppressor of cytokine signaling 3 (SOCS3), was a primary candidate region differentially hydrox [....] » Read More
Over the past 40 years, with the development of China's economy and changes in lifestyle, such as reduced physical activity, excessive energy intake, and the prevalence of overweight or obesity, the prevalence of diabetes in China has risen from 0.67% in 1980 to 12.4% in 2018 [....] » Read More
A comprehensive systematic review and meta-regression analysis, published in The Lancet Diabetes & Endocrinology, examined the relationship between the extent of bodyweight loss and the likelihood of type 2 diabetes remission. The study analyzed data from 22 randomized contro [....] » Read More
Diabetes is a prevalent disease in the United States, especially in elderly populations. It can either be caused by autoimmune complications (Type 1), poor dietary habits (Type 2), or damage to the pancreas (Type 3c). It is usually seen long-term and often comes with subsequent h [....] » Read More
Background: Hypoglycemia in non-diabetic individuals is uncommon and diagnostically challenging, especially in patients with prior upper gastrointestinal surgery. While dumping syndrome is often implicated in postprandial hypoglycemia, the presence of fasting hypoglycemia necessi [....] » Read More
This literature review synthesizes five decades of evidence on the U.S. obesity epidemic, tracing its rise from ~13% adult prevalence in the 1960s to >40% today and examining why the burden falls disproportionately on socioeconomically disadvantaged communities. The presenta [....] » Read More
Several studies have shown that genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) are highly associated with the development of type 2 diabetes mellitus (T2DM) and its associated complications in several populations. The aim of our study was to investigate the a [....] » Read More
Uncover the science supporting the profound influence of proper nutrition on menopausal and neurological senescent changes. Dr. Amy Gutman, an emergency medicine physician and researcher now focusing on preventative and functional medicine, delves into evidence-based science show [....] » Read More
Recent advances in artificial intelligence (AI) have enabled deeper insights into peptide-receptor interactions relevant to diabetes management. In a collaborative study between utR Biotech and Innoplexus, AI-based molecular modelling was employed to investigate the binding profi [....] » Read More
Vascular dementia is a common neurodegenerative disease. This dementia is caused by cerebral blood vessel dysfunctions. It has high morbidity and mortality. Diabetes is a leading factor in the development of this dementia. However, the essential roles, mechanisms and consequences [....] » Read More
Background: Dyslipidemia is a common comorbidity in type 2 diabetes mellitus (T2DM) and contributes to cardiovascular disease. Understanding the associations between anthropometric indices and lipid parameters is important for risk stratification. Methods: A cross-sectional st [....] » Read More
Introduction: An interesting issue that needs to be investigated is the effect of physical and mental fatigue on quality of life and medication adherence in patients with diabetes mellitus. Kuo et al. recently published a relevant secondary study in which it emerged that fatigue [....] » Read More
Metabolic disorders, including Type 1 and Type 2 Diabetes, are significant global health challenges. The CDC estimates that 37.3 million Americans have diabetes, and another 96 million adults are diagnosed with prediabetes each year. Among individuals in Stage 2 diabetes, 75% wil [....] » Read More
Identification: Patient 1 (Mother): A.P.F., female, 38 years old. History: Diagnosed with T1D at age 5, 33 years ago. Profession: Nurse, PhD in the area of Diabetes. Patient 2 (Daughter): C.F, female, 8 years old. History: Diagnosed with T1D 2 years ago, at age 6. [....] » Read More
We present Pebisut® (Carbohydrate Polymer with Zinc Oxide) a Medical Device II, the result of our 23 years of research and the invitation of the National Institute of Health of the United States (N.I.A.I.D.) to obtain Grants R01 and R21 to continue with the same research line [....] » Read More
Objective: To explore the preventive effect of pregnancy log records and management and the influence of maternal lifestyles on the incidence of gestational diabetes mellitus (GDM). Design: This prospective case–control study was conducted at a hospital in Beijing, China [....] » Read More
Background: Diabetes mellitus during pregnancy has adverse impact on mother and offspring. Methods: A retrospective cohort study was conducted in Beijing, China. All pregnant women who underwent routine prenatal care and delivered successfully, along with their offspring who h [....] » Read More
Background: Diabetes mellitus is a chronic metabolic disorder characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action or both. It is a major cause of mortality and morbidity w [....] » Read More
Red rice (Oryza sativa L.), widely consumed across Asia, is recognized for its rich nutritional profile and bioactive phytochemicals with potential health benefits. This study focused on the development of red rice-based functional foods and their efficacy in managing diabetes, [....] » Read More
The human gut microbiome plays a pivotal role in metabolism, energy regulation, and overall health. Emerging research suggests that microbial composition may influence obesity by affecting nutrient absorption, fat storage, inflammation, and appetite regulation. This presentation [....] » Read More
Obesity is a global health crisis, contributing to a rise in non-communicable diseases such as diabetes, cardiovascular disorders, and metabolic syndromes. Traditional approaches to obesity prevention and management often fall short in addressing the complexity of individual risk [....] » Read More
Introduction: Type 2 diabetes mellitus (T2D) results from genetic and environmental factors. While genetics have some influence on the onset of diabetes, it is mainly environmental factors, particularly lifestyle habits, that will determine its early onset. Indeed, lifestyle habi [....] » Read More
Background: Diabetes is a major global health concern, with T2DM accounting for 90% of cases. T2DM is marked by declining insulin secretion and resistance. Recent studies suggest insulin plus metformin may be more effective than oral agents plus metformin in preserving beta-cell [....] » Read More
Diabetes upsurge is closely linked to climate change due to environmental degradation, negatively impacting on agricultural production. Related lifestyle diseases include Hypertension and cancer. Diabetes is a pandemic, with huge economic burden, affecting close to 2.3 million pe [....] » Read More
Blood glucose regulation is a dynamic and ever present process in all of us, regardless of whether an individual has been diagnosed with diabetes or any related metabolic condition. Daily routines such as eating, exercising, sleeping, or even something as seemingly routine as dri [....] » Read More
We have been taught to believe that type 2 diabetes is result of insulin resistance. We know that glucose haemostasis is controlled by a variety of hormones The two most spoken of are insulin and glucagon, the former more so than the latter. Our talk will focus on these two hormo [....] » Read More
Presently, ACOG and ADA recommend OGTTs for screening for diagnosis of Gestational Diabetes Mellitus (GDM). However, the validity of OGTTs is being questioned because OGTT results vary daily due to changing total content as well as type of carbohydrate intake durin [....] » Read More
Solid organ transplantation, via multiple mechanisms, accentuates pre-existing diabetes mellitus and promotes de novo diabetes post-transplant. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1 RA) are novel, emerging diabetes [....] » Read More
Diabetic foot complications remain one of the leading causes of lower limb amputations globally. In this abstract, we present a structured clinical protocol designed to assess and stratify amputation risk in patients with diabetic foot syndrome. The methodology includes history-t [....] » Read More
This study investigates the association between the Social Vulnerability Index (SVI) and the development and progression of diabetic retinopathy (DR) among patients with type 2 diabetes mellitus (T2DM) in New Orleans. DR is a leading cause of vision loss in the United States, par [....] » Read More
This presentation, titled "Implementing Team-Based Strategies for Diabetes Control in Skilled Nursing Settings," addresses the critical need for enhanced diabetes care within skilled nursing facilities through the integration of Complex Adaptive Systems (CAS) theory. Di [....] » Read More
Background: Diabetes is a leading cause of visual impairment in the United States. Clinical guidelines recommend that adults with diabetes receive a comprehensive eye examination annually to detect and treat conditions such as diabetic retinopathy, diabetic macular edema, catarac [....] » Read More
Title : Diabetes reduction (pre diabetes and type 2) with integrative medicine
F Buck Willis, Christian College of Medicine, Belize
The CDC also reports that 35% of the American population in 2023 were diagnosed with Pre-Diabetes Mellitus (PDM) via HbA1c testing and half of that population are also obese. Currently it is estimated that 59,500,000 American adults currently have obesity with PDM).1 The purpose [....] » Read More
Title : Comparative outcomes of antihypertensive therapy in black vs non hispanic white patients with hypertension and cardiovascular disease
Anil Harrison, Midwestern University, United States
This retrospective, multicenter cohort study evaluated the comparative effectiveness of calcium channel blockers (CCBs), angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs), and thiazide diuretics in reducing cardiovascular events among hypertens [....] » Read More
Title : Evaluating the severity of acute pancreatitis in type 2 diabetes patients treated with incretin-based therapies versus insulin: A multicenter retrospective analysis using APACHE II
Anil Harrison, Midwestern University, United States
This multicenter retrospective study investigates whether incretin-based therapies (GLP-1 receptor agonists and DPP-4 inhibitors) influence the severity of acute pancreatitis compared to insulin in patients with type 2 diabetes mellitus. Using the APACHE II scoring system as a va [....] » Read More
Title : Where autoimmunity meets metabolism: Lifestyle strategies to slow accelerated aging
Neha Bhanusali, University of Central Florida, United States
Autoimmune diseases such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and Sjögren’s syndrome are increasingly recognized as conditions that accelerate biological aging. Chronic systemic inflammation, mitochondrial dysfunction, and telomere shorteni [....] » Read More