Diabetes is a term used to describe a group of conditions that impact upon the body’s ability to control blood glucose levels. In type-I diabetes (T1DM), the β-cells in the pancreas responsible for producing insulin are lost, typically from an attack from the immun.... » Read More
Dysmetabolic conditions related to insulin-resistance (IR) are amongst the most common cause of death globally and their primary prevention has become a compelling goal of public health-oriented strategies. In recent years, there has been a growing interest in those nat.... » Read More
Objectives There are only three main markers for the diagnosis and management of diabetes Mellitus. Fasting and post prandial blood sugar level gives the amount of glucose present during single point of time. On the other hand, HbA1c value reflects your average blood .... » Read More
Rising prevalence of diabetic retinopathy (DR) and diabetic macular edema represents significant burden in the society and raises challenges both in establishing effective screening and in enlargening the screening scope and mitigating the risk of DR progression. Our g.... » Read More
Statement of the Problem: Presently, the prevalence of non-communicable diseases is increasingly growing with the number of diabetic people expected to increase from 171 million in 2000 to 366 million in 2030. This is the main cause of morbidity and mortality all over t.... » Read More
According to the World Health Organization, diabetes is the direct cause of 1.5 million deaths annually. The adoption of healthy lifestyles, such as regular and consistent physical activity, plays an important role in reducing the prevalence of diabetes and its complica.... » Read More
Heart disease remains the number leading cause of death year after year. The increased risk factors are certainly related to cardiovascular conditions but are also significantly attributable to metabolic disease states. There are significant advances in cardiovascula.... » Read More
Diabetes mellitus can lead to long-standing complications in multiple arenas. An area that is often overlooked is implications for major surgery. Spinal decompression and fusions have unique challenges in the diabetic patient. In this review, we briefly highlight the pa.... » Read More
Background and aims: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting up to 13% of women of reproductive age. Although the underlying pathogenesis of PCOS has not been fully understood, there is increasing evidence that supports insulin r.... » Read More
Diabetes is a major public health concern that has been progressively rising worldwide. This disease is associated with a high rate of mortality, morbidity, and long-term consequences and remains a significant risk factor for cardiovascular disorders. Diabetes is a majo.... » Read More
Background: Diabetes is an incurable chronic disease caused by a deficiency or failure to use insulin leading to excess sugar in the blood. According to the WHO, diabetes remains a real public health problem, despite the prevention efforts implemented by the health syst.... » Read More
Diabetes sweet is defined by elevation chronicle of the concentration of glucose in the blood, to fasting 1.26 g/L or > 2g / L whatever collection time in presence of symptoms clinics, there are 2 types of diabetes: diabetes type1 and 2. An estimated 422 million adults .... » Read More
Background. Haptoglobin is an acute-phase inflammatory protein mainly produced by the liver. Although recent literature evidence that rs2000999 in the HP gene is associated with total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels in Mexicans, l.... » Read More
Brazil has approximately 20 million people with Diabetes Mellitus. Early identification and treatment should be a concern of public authorities, to improve glycemic control and reduce it`s deleterious impacts on the individual's health and consequent cost reduction for .... » Read More
Organic Chemists and Biochemist's attention is brought to the task of searching for enzymes and procedures to affect in vivo enzymatic ascending or descending glucose sugars into nontoxic high or low carbon sugars or in vivo superimposing mirror image glucose sugars i.... » Read More
Title : Heart failure management; a perspective from diabetes care
Baruch Itzhak, Tel Aviv University, Israel
People with type 2 diabetes (T2DM) are recognized as having a 2–4 times increased risk of heart failure (HF). Ambulatory diabetes care has long concentrated on the prevention of microvascular and arterial disease, and surveillance for manageable problems such as with th.... » Read More
Title : Epidemiological profile of diabetes, northeast, Haiti, 2017-2021
Kensly Flecher, Field Epidemiology Training Program (FETP), Haiti
Background: According to the WHO, diabetes is a public health problem. Its prevalence continues to increase over the years. The number of cases has increased worldwide from 108 million in 1980 to 537 million in 2021. In Haiti, 300,000 cases were reported in 2019. The pr.... » Read More
Title : Role of the abscisic acid/LANCL system in glycemic control: A promising aid to combat diabetes and related metabolic syndrome
Laura Sturla, University of Genova, Italy
Abscisic acid (ABA) is an isoprenoid hormone with a very long evolutionary history and the only known hormone common to the vegetal and animal kingdoms, with a conserved role as a signal regulating cell responses to environmental challenge. Nanomolar ABA is also present.... » Read More
Title : Gestational diabetes is associated with a distinct urinary metabolomic signature in the latter half of pregnancy
Aisling Murphy, University of California, United States
Introduction: Gestational diabetics (GD) have both impaired insulin sensitivity and secretion, which may lead to perturbations in multiple metabolic pathways. Currently, screening paradigms for gestational diabetes mellitus (GDM) rely on demonstration of hyperglycemia a.... » Read More
Title : Microsomal triglyceride transfer protein regulates intracellular lipolysis in adipocytes independent of its lipid transfer activity
Sujith Rajan, NYU Long Island School of Medicine, United States
Background: The triglyceride (TG) transfer activity of microsomal triglyceride transfer protein (MTP) is essential for lipoprotein assembly in the liver and intestine; however, its function in adipose tissue, which does not assemble lipoproteins, is unknown. Here we hav.... » Read More