The intricate relationship between metabolic disorders & obesity plays a pivotal role in diabetes pathogenesis. Excess adiposity, particularly visceral fat accumulation, promotes insulin resistance and chronic inflammation, increasing the likelihood of type 2 diabetes. Dysregulated lipid metabolism and hormonal imbalances further exacerbate metabolic dysfunction, contributing to conditions such as metabolic syndrome and non-alcoholic fatty liver disease. Emerging research highlights the role of gut microbiota and genetic predisposition in metabolic health. Novel therapeutic strategies, including GLP-1 receptor agonists, bariatric surgery, and personalized nutrition plans, are proving effective in managing obesity-driven metabolic disorders. A multidisciplinary approach integrating pharmacotherapy, lifestyle interventions, and early screening is essential for preventing disease progression.
Mahir Khalil Ibrahim Jallo
Gulf Medical University, Canada
Yong Xiao Wang
Albany Medical College, United States
F Buck Willis
University of Belize, Belize
Sujith Rajan
NYU Long Island School of Medicine, United States
Amy Gutman
AdventHealth; Tough Love MD, United States
Paraskevi Theofilou
Hellenic Open University, Greece
Teji S Dhami
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