Diabetes is one of the world's most critical health issues. Blood vessel disease, also known as angiopathy, is a severe consequence of diabetes that is characterized by aberrant angiogenesis. Angiogenesis is distinguished from vasculogenesis, which is de novo vessel formation from hematopoietic progenitor cells, Abnormal angiogenesis and atherosclerosis by the formation of new blood vessels from pre-existing vessels. Angiogenesis, on the other hand, is not always helpful and is frequently linked to pathologic diseases, in which case it is referred to as pathologic angiogenesis. The angiogenesis signal in diabetes is regulated differently depending on the organ, tissue, and cell type. Blood arteries that convey oxygen-rich blood away from the heart are affected. These vessels transport blood to various regions of the body.
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