Pathogenesis of Diabetes

The process through which a condition or disease develops is known as pathogenesis. It can comprise elements that contribute not only to the onset, but also to the development and maintenance of the disease or disorder. Diabetes mellitus is a metabolic condition with excessive hyperglycemia caused by a lack of insulin secretion or a combination of insulin resistance and insufficient insulin secretion to compensate. Diabetes type 1 is most commonly reported in children and adults. It occurs when the body's immune system attacks pancreatic beta cells, which are the only cells in the body that produce the hormone insulin, which controls blood glucose levels. Insulin resistance is frequently the major metabolic aberration that leads to type 2 diabetes development. Type 2 diabetes can be seen of as the result of a succession of pathophysiologic alterations, each of which puts the patient at risk for a disturbance of normal glucose homeostasis.

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